The lights should flash briefly indicating the unit is receiving power over the USB connection.
Plug in USB cable from vMix Control Surface to Computer. VMix Control Surface is compatible with all installations of vMix version 15 and beyond. Once installed, verify you have the latest version of vMix. Run the installer and accept the prompts to install. The following is a User Guide that describes the capabilities of each of the buttons and controls. VMix Control Surface is an optional hardware control surface for vMix that connects via USB.